A bioelectronic system for insulin release triggered by ketone body mimicking diabetic ketoacidosis in vitro.
نویسندگان
چکیده
A bioelectronic system composed of two modified electrodes, one activated in the presence of ketone bodies, a biomarker of diabetic ketoacidosis, and another releasing insulin upon receiving a signal, was designed and tested in vitro to operate as a Sense-and-Act device. The functional integration of biomarker-sensing and insulin-releasing electrodes represents a step to a theranostic system with autonomous operation.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 36 شماره
صفحات -
تاریخ انتشار 2015